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leuA protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"leuA" - Alpha-isopropylmalate synthase in Ruminococcus sp. 5139BFAA
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second shell of interactors
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filled nodes:
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
leuAAlpha-isopropylmalate synthase ; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (577 aa)    
Predicted Functional Partners:
leuB
Beta-IPM dehydrogenase ; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (360 aa)
   
  0.985
RSAG_03476
Isopropylmalate isomerase ; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (416 aa)
 
  0.981
RSAG_03474
Isopropylmalate isomerase ; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (415 aa)
 
  0.981
RSAG_03477
3-isopropylmalate dehydratase, small subunit (160 aa)
   
 
  0.962
RSAG_03475
3-isopropylmalate dehydratase small subunit (163 aa)
   
 
  0.962
ilvD
Dihydroxy-acid dehydratase (557 aa)
 
 
  0.956
RSAG_01545
Dihydroxy-acid dehydratase (581 aa)
   
 
  0.949
RSAG_01872
Branched-chain amino acid aminotransferase (341 aa)
   
  0.929
RSAG_02567
Acetolactate synthase (572 aa)
   
 
  0.928
RSAG_00355
Acetolactate synthase (563 aa)
   
 
  0.928
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
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