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RSAG_00951 protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"RSAG_00951" - Endonuclease IV in Ruminococcus sp. 5139BFAA
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
RSAG_00951Endonuclease IV ; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5’-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (278 aa)    
Predicted Functional Partners:
nth
DNA-(apurinic or apyrimidinic site) lyase ; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (215 aa)
   
 
  0.786
RSAG_03032
Exodeoxyribonuclease III (Xth) (251 aa)
     
  0.768
RSAG_01228
DNA polymerase I (849 aa)
     
 
  0.720
RSAG_00719
A/G-specific adenine glycosylase (352 aa)
     
   
  0.688
RSAG_01176
Exonuclease SbcCD, D subunit (1275 aa)
   
 
  0.601
RSAG_00950
Uncharacterized protein (132 aa)
              0.593
RSAG_03412
Uncharacterized protein (291 aa)
         
  0.582
RSAG_01058
Uncharacterized protein (280 aa)
         
  0.582
ung
Uracil-DNA glycosylase ; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (224 aa)
   
 
  0.576
topA
DNA topoisomerase I ; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (689 aa)
   
 
  0.553
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
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