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alaS protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"alaS" - Alanyl-tRNA synthetase in Ruminococcus sp. 5139BFAA
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
alaSAlanyl-tRNA synthetase ; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (879 aa)    
Predicted Functional Partners:
pheT
Phenylalanyl-tRNA synthetase beta subunit (805 aa)
   
 
  0.984
leuS
Leucyl-tRNA synthetase (800 aa)
   
 
  0.941
tyrS
Tyrosyl-tRNA synthetase ; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (409 aa)
   
 
  0.936
lysS
Lysyl-tRNA synthetase (678 aa)
 
 
  0.926
RSAG_01646
Methionine--tRNA ligase ; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (652 aa)
   
 
  0.909
ileS
Isoleucyl-tRNA synthetase ; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile) (1051 aa)
   
 
  0.883
RSAG_00514
Histidine-tRNA ligase (418 aa)
   
   
  0.880
valS
Valyl-tRNA synthetase ; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a "posttransfer" editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (884 aa)
 
   
  0.871
thrS
Threonyl-tRNA synthetase (653 aa)
 
 
  0.869
RSAG_03070
Uncharacterized protein (555 aa)
   
 
  0.856
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
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