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RSAG_01230 protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"RSAG_01230" - ATP-dependent zinc metalloprotease FtsH in Ruminococcus sp. 5139BFAA
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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RSAG_01230ATP-dependent zinc metalloprotease FtsH ; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (643 aa)    
Predicted Functional Partners:
grpE
HSP-70 cofactor ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- depend [...] (214 aa)
   
  0.863
groL
Protein Cpn60 ; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (539 aa)
   
 
  0.837
pth
Peptidyl-tRNA hydrolase ; The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (193 aa)
   
   
  0.784
RSAG_03213
Uncharacterized protein (220 aa)
 
 
  0.776
dnaK
Heat shock protein 70 ; Acts as a chaperone (625 aa)
 
  0.762
groS
Protein Cpn10 ; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (94 aa)
   
   
  0.727
RSAG_01754
Uncharacterized protein (394 aa)
   
 
  0.726
RSAG_01708
Uncharacterized protein (820 aa)
 
 
  0.715
RSAG_02686
F-ATPase subunit alpha ; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (502 aa)
   
 
  0.683
RSAG_02684
F-ATPase subunit beta ; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (465 aa)
     
  0.683
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
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