STRINGSTRING
hemC protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"hemC" - Pre-uroporphyrinogen synthase in Ruminococcus sp. 5139BFAA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemCPre-uroporphyrinogen synthase ; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (317 aa)    
Predicted Functional Partners:
RSAG_01242
Uroporphyrinogen-III C-methyltransferase (501 aa)
  0.999
RSAG_01241
Delta-aminolevulinic acid dehydratase (327 aa)
 
  0.996
hemA
Glutamyl-tRNA reductase ; Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (409 aa)
   
  0.993
hemL
Glutamate-1-semialdehyde aminotransferase (425 aa)
 
   
  0.986
RSAG_01244
Siroheme synthase domain-containing protein (165 aa)
 
 
  0.978
RSAG_01282
Precorrin-6x reductase (683 aa)
 
 
  0.833
RSAG_01285
Precorrin-4 C11-methyltransferase (258 aa)
     
  0.815
RSAG_02255
Precorrin-2 C20-methyltransferase (231 aa)
 
   
  0.811
cbiD
Cobalt-precorrin-6A synthase ; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A (388 aa)
   
 
  0.717
RSAG_00516
Coproporphyrinogen dehydrogenase HemZ (395 aa)
   
   
  0.648
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
Server load: low (7%) [HD]