STRINGSTRING
coaX protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"coaX" - Pantothenic acid kinase in Ruminococcus sp. 5139BFAA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaXPantothenic acid kinase ; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (254 aa)    
Predicted Functional Partners:
RSAG_01290
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate-cysteine ligase (402 aa)
 
 
  0.952
panC
Pantoate-activating enzyme ; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (279 aa)
   
 
  0.859
coaD
Pantetheine-phosphate adenylyltransferase ; Reversibly transfers an adenylyl group from ATP to 4’- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (164 aa)
   
   
  0.832
RSAG_03434
Uncharacterized protein (182 aa)
     
      0.644
RSAG_04639
Phosphopyruvate hydratase (301 aa)
     
      0.644
eno
2-phosphoglycerate dehydratase ; Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (433 aa)
     
      0.644
birA
Biotin-[acetyl-CoA carboxylase] synthetase ; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor (322 aa)
 
   
  0.584
RSAG_03174
Biotin-[acetyl-CoA-carboxylase] ligase (267 aa)
 
        0.582
valS
Valyl-tRNA synthetase ; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a "posttransfer" editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (884 aa)
 
          0.521
RSAG_03279
ATP-dependent zinc metalloprotease FtsH ; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (600 aa)
         
  0.481
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
Server load: low (6%) [HD]