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groS protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"groS" - Protein Cpn10 in Ruminococcus sp. 5139BFAA
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
groSProtein Cpn10 ; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (94 aa)    
Predicted Functional Partners:
groL
Protein Cpn60 ; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (539 aa)
 
  0.999
grpE
HSP-70 cofactor ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- depend [...] (214 aa)
   
 
  0.948
dnaK
Heat shock protein 70 ; Acts as a chaperone (625 aa)
 
 
  0.946
RSAG_01729
Uncharacterized protein (690 aa)
   
 
  0.936
tuf
Elongation factor Tu ; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (397 aa)
   
 
  0.852
RSAG_01708
Uncharacterized protein (820 aa)
 
 
  0.838
clpB
Chaperone protein ClpB ; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE (863 aa)
   
 
  0.813
clpP
Endopeptidase Clp ; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (193 aa)
 
 
  0.784
rpsJ
30S ribosomal protein S10 ; Involved in the binding of tRNA to the ribosomes (105 aa)
     
   
  0.783
RSAG_01855
Inosine-5’-monophosphate dehydrogenase (485 aa)
   
   
  0.776
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
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