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codY protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"codY" - GTP-sensing transcriptional pleiotropic repressor CodY in Ruminococcus sp. 5139BFAA
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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codYGTP-sensing transcriptional pleiotropic repressor CodY ; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (261 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I ; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (689 aa)
          0.930
RSAG_01196
UPF0122 protein RSAG_01196 ; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein (107 aa)
   
          0.680
RSAG_01345
Glutamine synthetase, type I (440 aa)
           
  0.617
ilvC
Alpha-keto-beta-hydroxylacyl reductoisomerase (339 aa)
           
  0.616
RSAG_01861
DNA protecting protein DprA (305 aa)
              0.586
RSAG_01862
Mg chelatase-like protein (510 aa)
              0.577
RSAG_01707
Uncharacterized protein (137 aa)
   
          0.548
RSAG_01400
Uncharacterized protein (752 aa)
   
     
  0.534
tsf
Elongation factor Ts ; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (312 aa)
 
     
  0.520
cysS
Cysteinyl-tRNA synthetase (469 aa)
           
  0.487
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
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