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tsaD protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"tsaD" - tRNA threonylcarbamoyladenosine biosynthesis protein TsaD in Ruminococcus sp. 5139BFAA
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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tsaDtRNA threonylcarbamoyladenosine biosynthesis protein TsaD ; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction (339 aa)    
Predicted Functional Partners:
RSAG_01973
Universal bacterial protein YeaZ (242 aa)
  0.997
RSAG_01974
YjeE family ATPase (144 aa)
 
  0.984
RSAG_01972
Ribosomal-protein-alanine acetyltransferase (145 aa)
 
      0.970
ispD
MEP cytidylyltransferase ; Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (230 aa)
 
        0.904
ksgA
S-adenosylmethionine-6-N’, N’-adenosyl(rRNA) dimethyltransferase ; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3’-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (290 aa)
 
   
  0.880
secA
Protein translocase subunit SecA ; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (858 aa)
 
   
  0.868
crcB
Putative fluoride ion transporter CrcB ; Important for reducing fluoride concentration in the cell, thus reducing its toxicity (121 aa)
     
      0.856
pheT
Phenylalanyl-tRNA synthetase beta subunit (805 aa)
 
   
  0.812
RSAG_01228
DNA polymerase I (849 aa)
 
   
  0.796
rnz
tRNase Z ; Zinc phosphodiesterase, which displays some tRNA 3’- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3’-trailer from precursor tRNA (302 aa)
   
        0.792
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
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