STRINGSTRING
RSAG_02730 protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"RSAG_02730" - Thiazole biosynthesis protein ThiH in Ruminococcus sp. 5139BFAA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSAG_02730Thiazole biosynthesis protein ThiH (413 aa)    
Predicted Functional Partners:
thiG
Thiazole synthase ; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (259 aa)
  0.999
RSAG_02729
Thiamine-phosphate pyrophosphorylase (198 aa)
 
   
  0.977
thiC
Thiamine biosynthesis protein ThiC ; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (436 aa)
 
 
  0.851
thiE
Thiamine-phosphate pyrophosphorylase ; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (212 aa)
   
   
  0.786
RSAG_00212
Pyruvate-flavodoxin oxidoreductase ; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (1178 aa)
 
     
  0.687
RSAG_02013
Phosphomethylpyrimidine kinase (269 aa)
   
   
  0.661
RSAG_00058
Hydrogenase maturation GTPase HydF (402 aa)
   
  0.657
RSAG_02659
5’-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2 ; Catalyzes the irreversible cleavage of the glycosidic bond in both 5’-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5’-methylthioribose and S-ribosylhomocysteine, respectively (232 aa)
         
  0.629
bioD
Dethiobiotin synthase ; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (232 aa)
         
  0.586
RSAG_00056
Iron-only hydrogenase maturation rSAM protein HydE (349 aa)
 
   
0.571
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
Server load: low (10%) [HD]