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infB protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"infB" - Translation initiation factor IF-2 in Ruminococcus sp. 5139BFAA
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
infBTranslation initiation factor IF-2 ; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (941 aa)    
Predicted Functional Partners:
infA
Translation initiation factor IF-1 ; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex (72 aa)
     
  0.980
rpsC
30S ribosomal protein S3 ; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (218 aa)
     
  0.973
RSAG_03045
Uncharacterized protein (112 aa)
   
  0.972
nusA
Transcription termination/antitermination protein NusA ; Participates in both transcription termination and antitermination (406 aa)
   
 
  0.970
rpsB
30S ribosomal protein S2 (247 aa)
 
  0.968
infC
Translation initiation factor IF-3 ; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (164 aa)
     
  0.960
RSAG_03046
Uncharacterized protein (91 aa)
   
   
  0.958
rpsO
30S ribosomal protein S15 ; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (88 aa)
 
 
  0.942
rbfA
Ribosome-binding factor A ; Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5’-terminal helix region of 16S rRNA (131 aa)
   
   
  0.930
rpsG
30S ribosomal protein S7 ; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (171 aa)
     
  0.927
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
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