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RSAG_03066 protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"RSAG_03066" - FolC protein in Ruminococcus sp. 5139BFAA
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
RSAG_03066FolC protein (427 aa)    
Predicted Functional Partners:
RSAG_01314
Dihydropteroate pyrophosphorylase ; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives (271 aa)
 
  0.986
RSAG_01313
7,8-dihydroneopterin aldolase ; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin (283 aa)
 
  0.969
folD
Bifunctional protein FolD ; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (284 aa)
 
  0.888
glyA
Serine hydroxymethyltransferase ; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (412 aa)
   
  0.870
fhs
Formyltetrahydrofolate synthetase (561 aa)
   
 
  0.860
RSAG_01873
Dihydrofolate reductase ; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (163 aa)
   
  0.850
RSAG_00521
Protein-export membrane protein SecD ; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (802 aa)
     
    0.838
RSAG_03065
Chorismate mutase (376 aa)
         
  0.827
folE
GTP cyclohydrolase I (185 aa)
 
 
  0.822
thyA
Thymidylate synthase ; Provides the sole de novo source of dTMP for DNA biosynthesis (282 aa)
     
 
  0.790
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
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