Genes that are sometimes fused into single open reading frames.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein (316 aa)
Predicted Functional Partners:
Uncharacterized protein (382 aa)
Uncharacterized protein (184 aa)
Uncharacterized protein (335 aa)
Peptidyl-tRNA hydrolase ; The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (193 aa)
Uncharacterized protein (813 aa)
Uncharacterized protein (409 aa)
Uncharacterized protein (365 aa)
Transcription-repair-coupling factor ; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site (1107 aa)