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cobB protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"cobB" - Regulatory protein SIR2 homolog in Ruminococcus sp. 5139BFAA
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
cobBRegulatory protein SIR2 homolog ; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form (240 aa)    
Predicted Functional Partners:
RSAG_02465
NAD+ synthetase (638 aa)
   
  0.858
RSAG_01176
Exonuclease SbcCD, D subunit (1275 aa)
   
 
  0.812
rplB
50S ribosomal protein L2 ; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (281 aa)
       
      0.741
tig
PPIase ; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (428 aa)
     
      0.719
nadD
Nicotinate mononucleotide adenylyltransferase ; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (211 aa)
   
  0.717
rplF
50S ribosomal protein L6 ; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center (179 aa)
       
      0.717
rplE
50S ribosomal protein L5 ; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (179 aa)
       
      0.717
RSAG_01197
Threonine dehydratase (403 aa)
       
      0.717
dnaK
Heat shock protein 70 ; Acts as a chaperone (625 aa)
       
    0.694
RSAG_01679
Uncharacterized protein (282 aa)
   
    0.692
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
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