Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein (57 aa)
Predicted Functional Partners:
Hydrogenase, Fe-only (562 aa)
Uncharacterized protein (1517 aa)
No annotation available (40 aa)
Dihydroorotate oxidase B, electron transfer subunit ; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+) (262 aa)
Uncharacterized protein (295 aa)
CO dehydrogenase/CO-methylating acetyl-CoA synthase complex, beta subunit (708 aa)
Dihydroorotate oxidase B, electron transfer subunit ; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+)
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Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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For the above enrichment analysis, the following statistical background is assumed: