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ksgA protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"ksgA" - S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase in Ruminococcus sp. 5139BFAA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ksgAS-adenosylmethionine-6-N’, N’-adenosyl(rRNA) dimethyltransferase ; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3’-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (290 aa)    
Predicted Functional Partners:
rpsD
30S ribosomal protein S4 ; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (197 aa)
     
 
  0.958
rpsH
30S ribosomal protein S8 ; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (133 aa)
 
 
  0.933
ispE
4-(cytidine-5’-diphospho)-2-C-methyl-D-erythritol kinase ; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (292 aa)
   
  0.932
rpsG
30S ribosomal protein S7 ; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (171 aa)
     
 
  0.925
rpsB
30S ribosomal protein S2 (247 aa)
     
 
  0.918
rpsI
30S ribosomal protein S9 (130 aa)
   
 
  0.887
RSAG_01855
Inosine-5’-monophosphate dehydrogenase (485 aa)
   
 
  0.882
tsaD
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD ; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction (339 aa)
 
   
  0.880
rpsK
30S ribosomal protein S11 ; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (131 aa)
     
 
  0.874
RSAG_03300
Uncharacterized protein (302 aa)
   
 
  0.873
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
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