STRINGSTRING
RSAG_03476 protein (Ruminococcus sp. 5139BFAA) - STRING interaction network
"RSAG_03476" - Isopropylmalate isomerase in Ruminococcus sp. 5139BFAA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSAG_03476Isopropylmalate isomerase ; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (416 aa)    
Predicted Functional Partners:
RSAG_03477
3-isopropylmalate dehydratase, small subunit (160 aa)
  0.999
RSAG_03475
3-isopropylmalate dehydratase small subunit (163 aa)
  0.999
leuB
Beta-IPM dehydrogenase ; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (360 aa)
 
  0.997
leuA
Alpha-isopropylmalate synthase ; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (577 aa)
 
  0.981
ilvD
Dihydroxy-acid dehydratase (557 aa)
 
 
  0.933
RSAG_00212
Pyruvate-flavodoxin oxidoreductase ; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (1178 aa)
   
 
  0.927
RSAG_00355
Acetolactate synthase (563 aa)
 
 
  0.909
RSAG_01545
Dihydroxy-acid dehydratase (581 aa)
 
 
  0.906
RSAG_02567
Acetolactate synthase (572 aa)
 
 
  0.900
RSAG_01658
Uncharacterized protein (580 aa)
 
 
  0.890
Your Current Organism:
Ruminococcus sp. 5139BFAA
NCBI taxonomy Id: 457412
Other names: R. sp. 5_1_39BFAA, Ruminococcus 5_1_39BFAA, Ruminococcus sp. 5139BFAA, Ruminococcus sp. 5_1_39BFAA
Server load: low (13%) [HD]