node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACB83745.1 | ACB84989.1 | Nther_0146 | Nther_1406 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | CheC, inhibitor of MCP methylation / FliN fusion protein; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: bld:BLi01853 flagellar motor switch protein. | 0.612 |
ACB83745.1 | ACB85497.1 | Nther_0146 | Nther_1926 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | PFAM: Ankyrin; KEGG: fps:FP2172 hypothetical protein. | 0.845 |
ACB83745.1 | ACB85919.1 | Nther_0146 | Nther_2354 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | KEGG: sth:STH3287 hypothetical protein. | 0.935 |
ACB83745.1 | dnaK | Nther_0146 | Nther_1183 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.972 |
ACB83745.1 | groL | Nther_0146 | Nther_0450 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.820 |
ACB83745.1 | groS | Nther_0146 | Nther_0449 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.865 |
ACB83745.1 | grpE | Nther_0146 | Nther_1182 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.927 |
ACB83745.1 | hrcA | Nther_0146 | Nther_1181 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.840 |
ACB83745.1 | hslU | Nther_0146 | Nther_1385 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.611 |
ACB83745.1 | htpG | Nther_0146 | Nther_0856 | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.886 |
ACB84989.1 | ACB83745.1 | Nther_1406 | Nther_0146 | CheC, inhibitor of MCP methylation / FliN fusion protein; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: bld:BLi01853 flagellar motor switch protein. | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | 0.612 |
ACB84989.1 | groL | Nther_1406 | Nther_0450 | CheC, inhibitor of MCP methylation / FliN fusion protein; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: bld:BLi01853 flagellar motor switch protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.864 |
ACB84989.1 | grpE | Nther_1406 | Nther_1182 | CheC, inhibitor of MCP methylation / FliN fusion protein; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: bld:BLi01853 flagellar motor switch protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.426 |
ACB85497.1 | ACB83745.1 | Nther_1926 | Nther_0146 | PFAM: Ankyrin; KEGG: fps:FP2172 hypothetical protein. | PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: bha:BH0103 class III stress response-related ATPase; Belongs to the ClpA/ClpB family. | 0.845 |
ACB85497.1 | ACB85919.1 | Nther_1926 | Nther_2354 | PFAM: Ankyrin; KEGG: fps:FP2172 hypothetical protein. | KEGG: sth:STH3287 hypothetical protein. | 0.989 |
ACB85497.1 | dnaK | Nther_1926 | Nther_1183 | PFAM: Ankyrin; KEGG: fps:FP2172 hypothetical protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.989 |
ACB85497.1 | groL | Nther_1926 | Nther_0450 | PFAM: Ankyrin; KEGG: fps:FP2172 hypothetical protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.855 |
ACB85497.1 | groS | Nther_1926 | Nther_0449 | PFAM: Ankyrin; KEGG: fps:FP2172 hypothetical protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.652 |
ACB85497.1 | grpE | Nther_1926 | Nther_1182 | PFAM: Ankyrin; KEGG: fps:FP2172 hypothetical protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.885 |
ACB85497.1 | hrcA | Nther_1926 | Nther_1181 | PFAM: Ankyrin; KEGG: fps:FP2172 hypothetical protein. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.704 |