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100280773 protein (Zea mays) - STRING interaction network
"100280773" - Replication protein A subunit in Zea mays
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
100280773Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (876 aa)    
Predicted Functional Partners:
mcm7
DNA helicase; Belongs to the MCM family (957 aa)
     
 
  0.917
100285903
OB-fold nucleic acid binding domain containing protein; Uncharacterized protein (336 aa)
     
 
  0.908
GRMZM2G018946_P04
Replication protein A 32 kDa subunit A; OB-fold nucleic acid binding domain containing protein; Uncharacterized protein (337 aa)
     
 
  0.908
GRMZM2G421493_P01
annotation not available (440 aa)
     
   
  0.832
100286018
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (562 aa)
     
   
  0.832
GRMZM2G072608_P01
Bifunctional dihydrofolate reductase-thymidylate synthase 2; Belongs to the dihydrofolate reductase family (300 aa)
     
   
  0.832
DRTS
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate- de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity) (523 aa)
     
   
  0.832
100304310
DNA helicase; Belongs to the MCM family (729 aa)
     
 
  0.827
pco076382
Replication protein A 32 kDa subunit A (307 aa)
     
 
  0.810
542504
DNA helicase; Belongs to the MCM family (720 aa)
     
 
  0.804
Your Current Organism:
Zea mays
NCBI taxonomy Id: 4577
Other names: Z. mays, Zea mays, Zea mays L., Zea mays var. japonica, maize
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