• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
pco111209 protein (Zea mays) - STRING interaction network
"pco111209" - Bifunctional TENA2 protein in Zea mays
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pco111209Bifunctional TENA2 protein; Involved in thiamine salvage by hydrolyzing the thiamine breakdown product 4-amino-5-aminomethyl-2-methylpyrimidine (amino- HMP) to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP). Has a high formylamino-HMP amidohydrolase activity. No activity with other thiamine degradation products such as thiamine mono- or diphosphate, oxothiamine, oxythiamine, thiamine disulfide, desthiothiamine or thiochrome as substrates. Does not display thiaminase II activity, as it is unable to hydrolyze thiamine. Is able to carry out two successive steps in the salvage of thiamin [...] (224 aa)    
Predicted Functional Partners:
732816
Phosphomethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase (551 aa)
   
 
  0.980
THIM
Hydroxyethylthiazole kinase; Thiazole kinase involved in thiamine salvage pathway (280 aa)
   
   
  0.940
100192785
5-formyltetrahydrofolate cyclo-ligase (179 aa)
           
  0.874
cl574_1
Hydroxymethylpyrimidine phosphate synthase1 (643 aa)
         
  0.818
nudix1
Nudix hydrolase 20 chloroplastic (353 aa)
         
  0.786
103653246
Thiaminase1 (425 aa)
           
  0.766
100216652
Purine-uracil permease NCS1 (541 aa)
           
  0.747
541828
Glutathione S-transferase; Uncharacterized protein ; Belongs to the GST superfamily (241 aa)
           
  0.730
tcp2
Mitochondrial thiamine diphosphate carrier 2; Mitochondrial transporter that mediates uptake of thiamine diphosphate (ThDP) into mitochondria (336 aa)
           
  0.699
pco141010b
Mitochondrial thiamine diphosphate carrier 1; Mitochondrial transporter that mediates uptake of thiamine diphosphate (ThDP) into mitochondria (336 aa)
           
  0.699
Your Current Organism:
Zea mays
NCBI taxonomy Id: 4577
Other names: Z. mays, Zea mays, Zea mays L., Zea mays var. japonica, maize
Server load: low (9%) [HD]