Groups of genes that are frequently observed in each other's genomic neighborhood.
Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
Genes that are sometimes fused into single open reading frames.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Putative purine permease 5; ATPUP5; Uncharacterized protein (376 aa)
Predicted Functional Partners:
Inositol transporter 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family (509 aa)
Esterase/lipase/thioesterase family protein (450 aa)
annotation not available (585 aa)
Uncharacterized protein (610 aa)
Tubulin alpha-4 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (452 aa)
Tubulin alpha-1 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (451 aa)
Tubulin alpha-3 chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (450 aa)
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NCBI taxonomy Id: 4577 Other names: Z. mays, Zea mays, Zea mays L., Zea mays var. japonica, maize