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NTH1 protein (Zea mays) - STRING interaction network
"NTH1" - Endonuclease III homolog in Zea mays
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N- glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines (291 aa)    
Predicted Functional Partners:
rad1
DNA repair endonuclease UVH1 (1851 aa)
   
 
  0.931
100192592
DNA excision repair protein ERCC-1 (397 aa)
     
 
  0.897
cl23743_1b
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (303 aa)
   
 
  0.868
100273912
N-glycosylase/DNA lyase OGG1 (419 aa)
   
 
  0.859
GRMZM2G425986_P01
A/G-specific adenine DNA glycosylase (701 aa)
   
   
  0.848
541878
Diphosphonucleotide phosphatase2 (512 aa)
       
 
  0.836
103632168
annotation not available (1531 aa)
   
 
  0.819
103634500
annotation not available (791 aa)
       
 
  0.807
GRMZM2G427067_P01
annotation not available (885 aa)
   
   
  0.803
100280412
Trehalase (598 aa)
           
  0.802
Your Current Organism:
Zea mays
NCBI taxonomy Id: 4577
Other names: Z. mays, Zea mays, Zea mays L., Zea mays var. japonica, maize
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