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100286018 protein (Zea mays) - STRING interaction network
"100286018" - Bifunctional dihydrofolate reductase-thymidylate synthase in Zea mays
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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100286018Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (562 aa)    
Predicted Functional Partners:
GRMZM2G044762_P01
annotation not available (222 aa)
   
  0.999
100285892
Deoxycytidylate deaminase; Uncharacterized protein (242 aa)
   
  0.998
tk1
Thymidine kinase (279 aa)
   
 
  0.997
103647875
Thymidylate kinase (255 aa)
   
 
  0.995
GRMZM6G314950_P01
DNA primase ; Belongs to the eukaryotic-type primase small subunit family (320 aa)
     
   
  0.994
GRMZM2G149802_P01
DNA polymerase (1528 aa)
     
   
  0.994
mcm7
DNA helicase; Belongs to the MCM family (957 aa)
     
   
  0.993
100285702
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family (587 aa)
   
 
  0.992
magi81248
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (263 aa)
   
 
  0.991
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (263 aa)
   
 
  0.991
Your Current Organism:
Zea mays
NCBI taxonomy Id: 4577
Other names: Z. mays, Zea mays, Zea mays L., Zea mays var. japonica, maize
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