Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Hypothetical protein LOC100274082 (287 aa)
Predicted Functional Partners:
DNA-directed RNA polymerase subunit beta’’ (EC 188.8.131.52)(PEP)(Plastid-encoded RNA polymerase subunit beta’’)(RNA polymerase subunit beta’’); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1527 aa)
DNA-directed RNA polymerase subunit beta’’ (EC 184.108.40.206)(PEP)(Plastid-encoded RNA polymerase subunit beta’’)(RNA polymerase subunit beta’’); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Hypothetical protein LOC100273912 (LOC100273912), mRNA
Hypothetical protein LOC100274082
DNA-3-methyladenine glycosylase 1
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Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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For the above enrichment analysis, the following statistical background is assumed: