Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
RING/U-box superfamily protein (247 aa)
Predicted Functional Partners:
Peroxisome assembly factor 1; Uncharacterized protein (337 aa)
Peroxisome biogenesis protein 12; Required for peroxisome biogenesis and for PTS1- and PTS2-dependent protein import into peroxisomes (394 aa)
Peroxisome biogenesis protein 7 (319 aa)
Peroxisome biogenesis protein 19-1; Peroxisomal biogenesis factor 19 (252 aa)
Peroxisomal biogenesis factor 19; Uncharacterized protein (253 aa)
Polyadenylate-binding protein; Binds the poly(A) tail of mRNA (735 aa)
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis (245 aa)
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis