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mez1 protein (Zea mays) - STRING interaction network
"mez1" - Histone-lysine N-methyltransferase EZ1 in Zea mays
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mez1Histone-lysine N-methyltransferase EZ1; Polycomb group (PcG) protein. Catalytic subunit of some PcG multiprotein complex, which methylates ’Lys-27’ of histone H3, leading to transcriptional repression of the affected target genes. PcG proteins are not required to initiate repression, but to maintain it during later stages of development (By similarity); Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. EZ subfamily (931 aa)    
Predicted Functional Partners:
fie1
Polycomb group protein FIE1; Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity); Belongs to the WD repeat ESC family (461 aa)
     
  0.990
fie2
Polycomb group protein FIE2; Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity) (401 aa)
     
  0.980
vef101a
Embryonic flower 2; VEF family protein (626 aa)
     
 
  0.967
gpm623
Polycomb group protein EMBRYONIC FLOWER 2 (607 aa)
     
 
  0.967
GRMZM2G149802_P01
DNA polymerase (1528 aa)
     
 
  0.946
crd101
Chromdomain-containing protein CRD101; Uncharacterized protein (380 aa)
       
 
  0.930
nfc103b
annotation not available (323 aa)
     
 
  0.903
nfc103
MSI type nucleosome/chromatin assembly factor C; Uncharacterized protein (601 aa)
     
 
  0.903
542545
annotation not available (261 aa)
     
 
  0.903
103650859
annotation not available (748 aa)
     
 
  0.888
Your Current Organism:
Zea mays
NCBI taxonomy Id: 4577
Other names: Z. mays, Zea mays, Zea mays L., Zea mays var. japonica, maize
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