Groups of genes that are frequently observed in each other's genomic neighborhood.
Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
Genes that are sometimes fused into single open reading frames.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Copper ion binding protein (154 aa)
Predicted Functional Partners:
Pollen extensin-like2; Extensin-like protein (1188 aa)
Pollen extensin-like2; Leucine-rich repeat (LRR) family protein (161 aa)
Leucine-rich repeat (LRR) family protein (427 aa)
Protein binding protein (442 aa)
Leucine-rich repeat (LRR) family protein; Uncharacterized protein (431 aa)
Leucine-rich repeat (LRR) family protein (548 aa)
Uncharacterized protein (245 aa)
Leucine-rich repeat (LRR) family protein; Uncharacterized protein (458 aa)
Auxin response factor; Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5’-TGTCTC-3’ found in the auxin-responsive promoter elements (AuxREs) (1053 aa)
Your Current Organism:
NCBI taxonomy Id: 4577 Other names: Z. mays, Zea mays, Zea mays L., Zea mays var. japonica, maize