STRINGSTRING
URM1 protein (Zea mays) - STRING interaction network
"URM1" - Ubiquitin-related modifier 1 homolog in Zea mays
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
URM1Ubiquitin-related modifier 1 homolog ; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2- thiolation reaction by being thiocarboxylated (-COSH) at its C- terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress s [...] (101 aa)    
Predicted Functional Partners:
UBA4-1
Adenylyltransferase and sulfurtransferase MOCS3 1 (Molybdenum cofactor synthesis protein 3 1) [Includes Adenylyltransferase MOCS3(EC 2.7.7.-)(Sulfur carrier protein MOCS2A adenylyltransferase)(EC 2.7.7.n4);Sulfurtransferase MOCS3(EC 2.8.1.-)(Sulfur carrier protein MOCS2A sulfurtransferase)(EC 2.8.1.n1)]; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-term [...] (468 aa)
       
  0.990
GRMZM2G347027_P01
Hypothetical protein LOC100280109 (441 aa)
       
  0.984
UBA4-2
Adenylyltransferase and sulfurtransferase MOCS3 2 (Molybdenum cofactor synthesis protein 3 2) [Includes Adenylyltransferase MOCS3(EC 2.7.7.-)(Sulfur carrier protein MOCS2A adenylyltransferase)(EC 2.7.7.n4);Sulfurtransferase MOCS3(EC 2.8.1.-)(Sulfur carrier protein MOCS2A sulfurtransferase)(EC 2.8.1.n1)]; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-term [...] (482 aa)
       
 
  0.953
GRMZM2G362306_P01
Hypothetical protein LOC100279201 ; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position (460 aa)
       
  0.879
GRMZM2G581155_P01
Uncharacterized protein (643 aa)
       
  0.854
GRMZM2G402242_P01
Hypothetical protein LOC100193637 (386 aa)
       
  0.854
GRMZM2G059700_P01
Hypothetical protein LOC100383482 (624 aa)
       
  0.854
GRMZM2G421857_P04
V-type proton ATPase catalytic subunit A Fragment (V-ATPase subunit A)(EC 3.6.3.14)(Vacuolar proton pump subunit alpha)(V-ATPase 69 kDa subunit); Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (851 aa)
       
      0.733
Zm.160505
V-type proton ATPase catalytic subunit A-like (622 aa)
       
      0.733
umc2783
Thioredoxin-like protein 1 (194 aa)
       
      0.733
Your Current Organism:
Zea mays
NCBI taxonomy Id: 4577
Other names: Euchlaena, Z. mays, Zea, Zea L., Zea mays, Zea mays L., Zea mays var. japonica, maize
Server load: low (9%) [HD]