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URM1 protein (Zea mays) - STRING interaction network
"URM1" - Ubiquitin-related modifier 1 homolog in Zea mays
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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URM1Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2- thiolation reaction by being thiocarboxylated (-COSH) at its C- terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress sp [...] (101 aa)    
Predicted Functional Partners:
tdsgR27H11
Adenylyltransferase and sulfurtransferase MOCS3 (441 aa)
     
  0.982
UBA4-1
Adenylyltransferase and sulfurtransferase MOCS3-1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (468 aa)
     
  0.982
MOCS3-2
Adenylyltransferase and sulfurtransferase MOCS3-2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (482 aa)
     
  0.982
100216575
Rhodanese-like/PpiC domain-containing protein 12 chloroplastic (57 aa)
     
 
  0.914
100194268
S-adenosyl-L-methionine-dependent methyltransferase superfamily protein (293 aa)
     
   
  0.889
100383086
Ubiquitinyl hydrolase 1; Ubiquitin carboxyl-terminal hydrolase (835 aa)
     
 
  0.866
pco115798
SUMO-activating enzyme subunit 1B-2; Ubiquitin-like 1-activating enzyme E1A; Uncharacterized protein (333 aa)
     
 
  0.855
100285075
Ubiquitin-fold modifier 1; Ubiquitin-like modifier (98 aa)
     
   
  0.839
IDP267
Elongator complex protein 1; Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation (1334 aa)
       
 
  0.838
GRMZM2G042371_P01
Elongator complex protein 2 (717 aa)
     
 
  0.834
Your Current Organism:
Zea mays
NCBI taxonomy Id: 4577
Other names: Z. mays, Zea mays, Zea mays L., Zea mays var. japonica, maize
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