Groups of genes that are frequently observed in each other's genomic neighborhood.
Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Hydroxycinnamoyltransferase12; Acyltransferase; Uncharacterized protein (444 aa)
Predicted Functional Partners:
Protein BRANCHLESS TRICHOME (306 aa)
Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs (378 aa)
Soluble diacylglycerol acyltransferase (411 aa)
Glycerol-3-phosphate acyltransferase 8 (515 aa)
Glossy13; Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily (1431 aa)