STRINGSTRING
MTHFR protein (Zea mays) - STRING interaction network
"MTHFR" - Methylenetetrahydrofolate reductase 1 (EC 1.5.1.20)(ZmMTHFR1) in Zea mays
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
MTHFRMethylenetetrahydrofolate reductase 1 (EC 1.5.1.20)(ZmMTHFR1); The probable reversibility of the MTHFR reaction in plants suggests that they can metabolize the methyl group of 5,10- methylenetetrahydrofolate to serine, sugars and starch (593 aa)    
Predicted Functional Partners:
GRMZM2G452630_P02
Hypothetical protein LOC100191532 (588 aa)
   
 
  0.965
GRMZM2G427836_P01
Annotation not available (109 aa)
   
 
  0.965
CL9311_1
Uncharacterized LOC100286146 (EC-2.1.2.1) (361 aa)
   
 
  0.965
IDP232
Hypothetical protein LOC100279332 ; The glycine cleavage system catalyzes the degradation of glycine (432 aa)
   
 
  0.961
Zm.96157
Bifunctional dihydrofolate reductase-thymidylate synthase ; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (562 aa)
     
 
  0.954
Zm.45026
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (765 aa)
   
  0.953
GRMZM2G149751_P05
Putative uncharacterized protein (781 aa)
   
  0.953
Zm.87255
Putative uncharacterized protein (812 aa)
   
  0.953
GRMZM2G091247_P01
Annotation not available (71 aa)
   
  0.953
GRMZM2G157586_P01
Annotation not available (72 aa)
     
 
  0.940
Your Current Organism:
Zea mays
NCBI taxonomy Id: 4577
Other names: Euchlaena, Z. mays, Zea, Zea L., Zea mays, Zea mays L., Zea mays var. japonica, maize
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