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csu134 protein (Zea mays) - STRING interaction network
"csu134" - Methylenetetrahydrofolate reductase 1 in Zea mays
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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Experiments
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[Homology]
Score
csu134Methylenetetrahydrofolate reductase 1; The probable reversibility of the MTHFR reaction in plants suggests that they can metabolize the methyl group of 5,10- methylenetetrahydrofolate to serine, sugars and starch (593 aa)    
Predicted Functional Partners:
DRTS
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate- de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity) (523 aa)
   
 
  0.985
GRMZM2G421493_P01
annotation not available (440 aa)
   
 
  0.977
100286018
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (562 aa)
   
 
  0.977
GRMZM2G072608_P01
Bifunctional dihydrofolate reductase-thymidylate synthase 2; Belongs to the dihydrofolate reductase family (300 aa)
   
 
  0.977
IDP232
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family (432 aa)
   
 
  0.964
GRMZM2G135283_P04
Serine hydroxymethyltransferase (513 aa)
   
 
  0.958
GRMZM2G039238_P01
Serine hydroxymethyltransferase; Interconversion of serine and glycine; Belongs to the SHMT family (538 aa)
   
 
  0.957
gly1
Serine hydroxymethyltransferase; Interconversion of serine and glycine; Belongs to the SHMT family (526 aa)
   
 
  0.955
100191532
Serine hydroxymethyltransferase 7 (588 aa)
   
 
  0.946
100286153
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (765 aa)
   
 
  0.930
Your Current Organism:
Zea mays
NCBI taxonomy Id: 4577
Other names: Z. mays, Zea mays, Zea mays L., Zea mays var. japonica, maize
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