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STRINGSTRING
100273582 protein (Zea mays) - STRING interaction network
"100273582" - DNA topoisomerase in Zea mays
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
100273582DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (915 aa)    
Predicted Functional Partners:
100216934
Crossover junction endonuclease MUS81 (186 aa)
   
 
  0.954
100278570
Putative DUF1767 domain containing protein (430 aa)
     
 
  0.937
100274706
ATP-dependent DNA helicase Q-like 4A (750 aa)
   
 
  0.934
rad1
DNA repair endonuclease UVH1 (1851 aa)
   
 
  0.933
103650756
annotation not available (450 aa)
   
 
  0.922
100274087
RecQ-mediated genome instability protein 1 (678 aa)
     
   
  0.896
103654570
DEAD/DEAH box RNA helicase family protein (537 aa)
     
 
  0.880
GRMZM2G035068_P01
DEAD/DEAH box RNA helicase family protein (930 aa)
     
 
  0.880
GRMZM2G039683_P03
ATP-dependent DNA helicase Q-like 3 (407 aa)
   
 
  0.874
GRMZM2G306348_P01
ATP-dependent DNA helicase Q-like 5 (1256 aa)
   
 
  0.864
Your Current Organism:
Zea mays
NCBI taxonomy Id: 4577
Other names: Z. mays, Zea mays, Zea mays L., Zea mays var. japonica, maize
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