Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Rhomboid-like protein (194 aa)
Predicted Functional Partners:
TraB protein (422 aa)
Cytochrome c oxidase subunit II (510 aa)
39S ribosomal protein L47 isoform 1; 39S ribosomal protein L47 isoform 2; Uncharacterized protein (138 aa)
RHOMBOID-like protein 12 mitochondrial (328 aa)
Translocase of chloroplast; GTPase involved in protein precursor import into chloroplasts. Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis (326 aa)
Ribosomal protein L22p/L17e family protein; Belongs to the universal ribosomal protein uL22 family (314 aa)
RHOMBOID-like protein 13; Putative Rhomboid family protein; Rhomboid family protein; Uncharacterized protein (275 aa)