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STRINGSTRING
PARP1 protein (Zea mays) - STRING interaction network
"PARP1" - Poly [ADP-ribose] polymerase 1 in Zea mays
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP1Poly [ADP-ribose] polymerase 1; Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (By similarity) (980 aa)    
Predicted Functional Partners:
cl55281_1
Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks (907 aa)
     
 
  0.959
100283527
DNA repair protein XRCC1; Uncharacterized protein (351 aa)
     
 
  0.958
100280315
Poly(ADP-ribose) glycohydrolase 1 (518 aa)
       
 
  0.920
PARP2
Poly [ADP-ribose] polymerase 2; Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (By similarity) (372 aa)
     
0.916
pco139890
ATP-dependent DNA helicase 2 subunit KU80; Single-stranded DNA-dependent ATP-dependent helicase (681 aa)
     
 
  0.905
GRMZM2G360455_P01
Protein phosphatase 2C isoform gamma (907 aa)
     
 
  0.860
103627237
annotation not available (836 aa)
         
0.843
100381612
Structural maintenance of chromosomes protein 5 (1057 aa)
     
   
  0.829
GRMZM5G863846_P01
annotation not available (147 aa)
     
 
  0.828
GRMZM5G851753_P01
annotation not available (97 aa)
     
 
  0.815
Your Current Organism:
Zea mays
NCBI taxonomy Id: 4577
Other names: Z. mays, Zea mays, Zea mays L., Zea mays var. japonica, maize
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