STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (283 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
 0.998
Shal_3200
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
   
 0.951
Shal_2801
PFAM: Pyridoxal-dependent decarboxylase; KEGG: slo:Shew_2535 pyridoxal-dependent decarboxylase.
  
 
 0.943
Shal_3043
TIGRFAM: glutamate decarboxylase; PFAM: Pyridoxal-dependent decarboxylase; KEGG: vfi:VF1064 glutamate decarboxylase; Belongs to the group II decarboxylase family.
  
 
 0.943
Shal_0986
PFAM: aminotransferase class-III; KEGG: slo:Shew_0966 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.920
coaA
TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: slo:Shew_0143 pantothenate kinase.
    
 0.919
cmk
KEGG: slo:Shew_1953 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
      0.911
Shal_1002
TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; KEGG: shn:Shewana3_3091 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.906
Shal_0428
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
 0.889
Shal_0751
KEGG: shm:Shewmr7_3295 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK.
 
   
 0.682
Your Current Organism:
Shewanella halifaxensis
NCBI taxonomy Id: 458817
Other names: S. halifaxensis HAW-EB4, Shewanella halifaxensis HAW-EB4, Shewanella halifaxensis str. HAW-EB4, Shewanella halifaxensis strain HAW-EB4
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