node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Shal_0002 | Shal_0402 | Shal_0002 | Shal_0402 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: ERCC4 domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: spc:Sputcn32_3619 ERCC4 domain protein. | 0.820 |
Shal_0002 | Shal_0436 | Shal_0002 | Shal_0436 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: shw:Sputw3181_0372 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases. | 0.728 |
Shal_0002 | Shal_1741 | Shal_0002 | Shal_1741 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: ATP dependent DNA ligase; KEGG: sbm:Shew185_1838 ATP dependent DNA ligase. | 0.983 |
Shal_0002 | Shal_2222 | Shal_0002 | Shal_2222 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase, RecQ family; KEGG: pin:Ping_3396 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases. | 0.728 |
Shal_0002 | Shal_2729 | Shal_0002 | Shal_2729 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: she:Shewmr4_2469 DNA polymerase B region. | 0.986 |
Shal_0002 | mutS | Shal_0002 | Shal_1231 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.976 |
Shal_0002 | recA | Shal_0002 | Shal_1232 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.927 |
Shal_0002 | xni | Shal_0002 | Shal_3066 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.916 |
Shal_0402 | Shal_0002 | Shal_0402 | Shal_0002 | PFAM: ERCC4 domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: spc:Sputcn32_3619 ERCC4 domain protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.820 |
Shal_0402 | Shal_0436 | Shal_0402 | Shal_0436 | PFAM: ERCC4 domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: spc:Sputcn32_3619 ERCC4 domain protein. | KEGG: shw:Sputw3181_0372 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases. | 0.851 |
Shal_0402 | Shal_1200 | Shal_0402 | Shal_1200 | PFAM: ERCC4 domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: spc:Sputcn32_3619 ERCC4 domain protein. | PFAM: metallophosphoesterase; KEGG: slo:Shew_1182 metallophosphoesterase. | 0.503 |
Shal_0402 | Shal_2222 | Shal_0402 | Shal_2222 | PFAM: ERCC4 domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: spc:Sputcn32_3619 ERCC4 domain protein. | ATP-dependent DNA helicase, RecQ family; KEGG: pin:Ping_3396 23S rRNA (Gm2251)-methyltransferase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases. | 0.851 |
Shal_0402 | Shal_2729 | Shal_0402 | Shal_2729 | PFAM: ERCC4 domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: spc:Sputcn32_3619 ERCC4 domain protein. | PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: she:Shewmr4_2469 DNA polymerase B region. | 0.772 |
Shal_0402 | mutS | Shal_0402 | Shal_1231 | PFAM: ERCC4 domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: spc:Sputcn32_3619 ERCC4 domain protein. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.727 |
Shal_0402 | recA | Shal_0402 | Shal_1232 | PFAM: ERCC4 domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: spc:Sputcn32_3619 ERCC4 domain protein. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.858 |
Shal_0402 | sbcD | Shal_0402 | Shal_2704 | PFAM: ERCC4 domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: spc:Sputcn32_3619 ERCC4 domain protein. | Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.503 |
Shal_0402 | xni | Shal_0402 | Shal_3066 | PFAM: ERCC4 domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: spc:Sputcn32_3619 ERCC4 domain protein. | 5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.852 |
Shal_0436 | Shal_0002 | Shal_0436 | Shal_0002 | KEGG: shw:Sputw3181_0372 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.728 |
Shal_0436 | Shal_0402 | Shal_0436 | Shal_0402 | KEGG: shw:Sputw3181_0372 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases. | PFAM: ERCC4 domain protein; SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: spc:Sputcn32_3619 ERCC4 domain protein. | 0.851 |
Shal_0436 | Shal_1200 | Shal_0436 | Shal_1200 | KEGG: shw:Sputw3181_0372 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases. | PFAM: metallophosphoesterase; KEGG: slo:Shew_1182 metallophosphoesterase. | 0.842 |