node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mnod_1252 | Mnod_1527 | Mnod_1252 | Mnod_1527 | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: met:M446_1995 KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | PFAM: protein of unknown function DUF1009; KEGG: met:M446_0644 hypothetical protein. | 0.748 |
Mnod_1252 | Mnod_7564 | Mnod_1252 | Mnod_7564 | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: met:M446_1995 KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.882 |
Mnod_1252 | bamA | Mnod_1252 | Mnod_1531 | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: met:M446_1995 KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.409 |
Mnod_1252 | kdsB | Mnod_1252 | Mnod_0512 | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: met:M446_1995 KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.896 |
Mnod_1252 | lpxA | Mnod_1252 | Mnod_1528 | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: met:M446_1995 KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.866 |
Mnod_1252 | lpxB | Mnod_1252 | Mnod_1526 | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: met:M446_1995 KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.865 |
Mnod_1252 | lpxC | Mnod_1252 | Mnod_7435 | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: met:M446_1995 KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.870 |
Mnod_1252 | lpxD | Mnod_1252 | Mnod_1530 | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: met:M446_1995 KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.864 |
Mnod_1252 | lpxK | Mnod_1252 | Mnod_7565 | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: met:M446_1995 KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.888 |
Mnod_1527 | Mnod_1252 | Mnod_1527 | Mnod_1252 | PFAM: protein of unknown function DUF1009; KEGG: met:M446_0644 hypothetical protein. | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: met:M446_1995 KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.748 |
Mnod_1527 | Mnod_7564 | Mnod_1527 | Mnod_7564 | PFAM: protein of unknown function DUF1009; KEGG: met:M446_0644 hypothetical protein. | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.787 |
Mnod_1527 | bamA | Mnod_1527 | Mnod_1531 | PFAM: protein of unknown function DUF1009; KEGG: met:M446_0644 hypothetical protein. | Outer membrane protein assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.531 |
Mnod_1527 | fabZ | Mnod_1527 | Mnod_1529 | PFAM: protein of unknown function DUF1009; KEGG: met:M446_0644 hypothetical protein. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.829 |
Mnod_1527 | kdsB | Mnod_1527 | Mnod_0512 | PFAM: protein of unknown function DUF1009; KEGG: met:M446_0644 hypothetical protein. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.746 |
Mnod_1527 | lpxA | Mnod_1527 | Mnod_1528 | PFAM: protein of unknown function DUF1009; KEGG: met:M446_0644 hypothetical protein. | acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.952 |
Mnod_1527 | lpxB | Mnod_1527 | Mnod_1526 | PFAM: protein of unknown function DUF1009; KEGG: met:M446_0644 hypothetical protein. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.968 |
Mnod_1527 | lpxC | Mnod_1527 | Mnod_7435 | PFAM: protein of unknown function DUF1009; KEGG: met:M446_0644 hypothetical protein. | UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.781 |
Mnod_1527 | lpxD | Mnod_1527 | Mnod_1530 | PFAM: protein of unknown function DUF1009; KEGG: met:M446_0644 hypothetical protein. | UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.887 |
Mnod_1527 | lpxK | Mnod_1527 | Mnod_7565 | PFAM: protein of unknown function DUF1009; KEGG: met:M446_0644 hypothetical protein. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.822 |
Mnod_7564 | Mnod_1252 | Mnod_7564 | Mnod_1252 | Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: met:M446_1995 KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.882 |