STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (392 aa)    
Predicted Functional Partners:
Mnod_4918
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.957
Mnod_5017
PFAM: homocysteine S-methyltransferase; KEGG: amr:AM1_0903 homocysteine S-methyltransferase, putative.
     
 0.933
Mnod_5459
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: met:M446_0251 cystathionine gamma-synthase.
  
 0.929
Mnod_3594
PFAM: C-5 cytosine-specific DNA methylase; KEGG: ppu:PP_1541 methyltransferase, putative.
    
 0.914
Mnod_3920
TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: pmy:Pmen_4036 DNA-cytosine methyltransferase.
    
 0.914
Mnod_4984
TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: pmy:Pmen_4036 DNA-cytosine methyltransferase.
    
 0.914
Mnod_6992
TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: oan:Oant_1510 DNA-cytosine methyltransferase.
    
 0.914
Mnod_7048
TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: pmy:Pmen_4036 DNA-cytosine methyltransferase.
    
 0.914
Mnod_0941
PFAM: autoinducer synthesis protein; KEGG: bbt:BBta_p0259 autoinducer synthesis protein TraI (conjugation factor synthetase).
     
 0.902
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 
 0.894
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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