STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepAProbable cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (503 aa)    
Predicted Functional Partners:
pepN
Aminopeptidase N (Alpha-aminoacylpeptide hydrolase); silverDB:etchr02110.
   
 0.936
rimK
Glutathione synthase/Ribosomal protein S6 modification enzyme(glutaminyl transferase); silverDB:etchr02819; Belongs to the prokaryotic GSH synthase family.
   
 
 0.921
pepB
Peptidase B (Aminopeptidase B); Probably plays an important role in intracellular peptide degradation.
  
  
 
0.920
pepD
Aminoacyl-histidine dipeptidase (Peptidase D), gene: pepD; silverDB:etchr02587.
   
 
 0.918
ggt-3
Gamma-glutamyltranspeptidase; silverDB:etchr03245.
     
 0.909
gshA
Glutamate-cysteine ligase; silverDB:etchr02650; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
 0.907
chaC
Cation transport protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
  0.900
aspC
Aspartate aminotransferase; silverDB:etchr02114.
    
 0.822
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.820
cysK
Cysteine synthase A; silverDB:etchr01091; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.816
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.