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nfo protein (Erwinia tasmaniensis) - STRING interaction network
"nfo" - Probable endonuclease 4 in Erwinia tasmaniensis
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nfoProbable endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5’-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (280 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (929 aa)
   
 
  0.718
mutY
A/G-specific adenine glycosylase; silverDB-etchr02834 (361 aa)
     
   
  0.711
yeiH
Putative inner membrane protein YeiH; silverDB-etchr01268; Belongs to the UPF0324 family (351 aa)
              0.705
alkA
Putative DNA-3-methyladenine glycosidase II; silverDB-etchr02278 (483 aa)
     
 
  0.663
xthA
Exodeoxyribonuclease III; silverDB-etchr01559 (268 aa)
     
 
  0.556
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (211 aa)
   
 
  0.553
yeiE
Transcriptional regulator YeiE; silverDB-etchr01269 (291 aa)
 
        0.529
yjeF
Multifunctional fusion protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration; Belongs to the NnrD/CARKD family (506 aa)
     
        0.461
argR
Arginine repressor; Regulates arginine biosynthesis genes (156 aa)
           
  0.449
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (355 aa)
     
 
  0.435
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
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