node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
coaD | xseB | ETA_00700 | ETA_25250 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Probable exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.436 |
dxs | ispA | ETA_25270 | ETA_25260 | 1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Geranyltranstransferase; silverDB:etchr02514; Belongs to the FPP/GGPP synthase family. | 0.945 |
dxs | thiI | ETA_25270 | ETA_25240 | 1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.688 |
dxs | xseB | ETA_25270 | ETA_25250 | 1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Probable exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.897 |
hemC | ispA | ETA_02120 | ETA_25260 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Geranyltranstransferase; silverDB:etchr02514; Belongs to the FPP/GGPP synthase family. | 0.419 |
hemC | ispB | ETA_02120 | ETA_03300 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Octaprenyl diphosphate synthase; silverDB:etchr00329; Belongs to the FPP/GGPP synthase family. | 0.450 |
hemC | xseB | ETA_02120 | ETA_25250 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Probable exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.530 |
ispA | dxs | ETA_25260 | ETA_25270 | Geranyltranstransferase; silverDB:etchr02514; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.945 |
ispA | hemC | ETA_25260 | ETA_02120 | Geranyltranstransferase; silverDB:etchr02514; Belongs to the FPP/GGPP synthase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.419 |
ispA | ispB | ETA_25260 | ETA_03300 | Geranyltranstransferase; silverDB:etchr02514; Belongs to the FPP/GGPP synthase family. | Octaprenyl diphosphate synthase; silverDB:etchr00329; Belongs to the FPP/GGPP synthase family. | 0.925 |
ispA | thiI | ETA_25260 | ETA_25240 | Geranyltranstransferase; silverDB:etchr02514; Belongs to the FPP/GGPP synthase family. | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.527 |
ispA | xseA | ETA_25260 | ETA_10340 | Geranyltranstransferase; silverDB:etchr02514; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.573 |
ispA | xseB | ETA_25260 | ETA_25250 | Geranyltranstransferase; silverDB:etchr02514; Belongs to the FPP/GGPP synthase family. | Probable exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.937 |
ispB | hemC | ETA_03300 | ETA_02120 | Octaprenyl diphosphate synthase; silverDB:etchr00329; Belongs to the FPP/GGPP synthase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.450 |
ispB | ispA | ETA_03300 | ETA_25260 | Octaprenyl diphosphate synthase; silverDB:etchr00329; Belongs to the FPP/GGPP synthase family. | Geranyltranstransferase; silverDB:etchr02514; Belongs to the FPP/GGPP synthase family. | 0.925 |
ispB | xseB | ETA_03300 | ETA_25250 | Octaprenyl diphosphate synthase; silverDB:etchr00329; Belongs to the FPP/GGPP synthase family. | Probable exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.533 |
mfd | recJ | ETA_20060 | ETA_27850 | Transcription-repair coupling factor (ATP-dependent helicase mfd); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Single-stranded-DNA-specific exonuclease; silverDB:etchr02773. | 0.598 |
mfd | xseA | ETA_20060 | ETA_10340 | Transcription-repair coupling factor (ATP-dependent helicase mfd); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.618 |
mfd | xseB | ETA_20060 | ETA_25250 | Transcription-repair coupling factor (ATP-dependent helicase mfd); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Probable exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.450 |
recJ | mfd | ETA_27850 | ETA_20060 | Single-stranded-DNA-specific exonuclease; silverDB:etchr02773. | Transcription-repair coupling factor (ATP-dependent helicase mfd); Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.598 |