STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FGIG_11092Uncharacterized protein. (1127 aa)    
Predicted Functional Partners:
FGIG_08233
Poly [ADP-ribose] polymerase.
    
 0.814
FGIG_02730
Poly [ADP-ribose] polymerase.
    
 0.814
FGIG_06767
Poly [ADP-ribose] polymerase.
    
 0.814
FGIG_11300
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
   0.685
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
     
 0.596
FGIG_02873
Histone H2A; Belongs to the histone H2A family.
      
 0.588
FGIG_04805
Macro domain-containing protein.
      
 0.588
FGIG_01907
Uncharacterized protein.
     
 0.552
FGIG_11019
Enkurin domain-containing protein.
     
 0.550
FGIG_11785
Putative xp-G/rad2 DNA repair endonuclease family member.
     
 0.515
Your Current Organism:
Fasciola gigantica
NCBI taxonomy Id: 46835
Other names: F. gigantica
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