STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FGIG_00449Cyclin-dependent kinase 6. (860 aa)    
Predicted Functional Partners:
FGIG_08865
G1/S-specific cyclin-D2; Belongs to the cyclin family.
   
 0.995
FGIG_00650
Cyclin B; Belongs to the cyclin family.
   
 0.994
FGIG_07524
G2/mitotic-specific cyclin-B3; Belongs to the cyclin family.
   
 0.994
FGIG_02103
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.992
FGIG_07931
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.991
FGIG_03258
Wee1 protein kinase.
   
 0.990
FGIG_07316
Putative retinoblastoma protein.
   
 0.984
FGIG_06656
Anaphase-promoting complex subunit 8.
    
 0.956
FGIG_11300
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.955
FGIG_11735
Fizzy protein.
   
 0.953
Your Current Organism:
Fasciola gigantica
NCBI taxonomy Id: 46835
Other names: F. gigantica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.