STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpdBPeriplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family. (658 aa)    
Predicted Functional Partners:
JP75_19155
5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family.
 
 
 
0.948
JP75_24725
5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family.
  
 
 
0.907
JP75_11730
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
    
  0.878
surE
Hypothetical protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.878
JP75_24045
Nucleoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.874
JP75_11725
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
   
 
 0.848
JP75_08555
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.807
JP75_12145
Nucleoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.807
JP75_20700
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.807
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.776
Your Current Organism:
Devosia riboflavina
NCBI taxonomy Id: 46914
Other names: ATCC 9526, CIP 59.10, D. riboflavina, DSM 7230, IFO 13584, JCM 21244, LMG 2277, LMG:2277, NBRC 13584, NRRL B-2463, NRRL B-784, Pseudomonas riboflavina, strain Foster strain 4R3337
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.