STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Coexpression
Experiments
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[Homology]
Score
fabH3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (318 aa)    
Predicted Functional Partners:
Tbis_2369
PFAM: Acyl transferase; KEGG: eba:ebA5456 acyl-carrier-protein S- malonyltransferase.
 
 
 0.999
Tbis_2372
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.999
Tbis_2222
PFAM: carboxyl transferase; KEGG: acetyl-coA carboxylase; K01959 pyruvate carboxylase subunit A.
 
  
 0.980
Tbis_0691
PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; phosphoribosylglycinamide synthetase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: biotin carboxylase; K01946 biotin carboxylase.
 
 
 0.977
Tbis_2153
PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; biotin carboxylase domain protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; RimK domain protein ATP-grasp; biotin/lipoyl attachment domain- containing protein; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: rpt:Rpal_2809 carbamoyl-phosphate synthase L chain ATP-binding.
 
 
 0.976
Tbis_2524
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: azc:AZC_2061 short-chain dehydrogenase.
 
 
 0.968
plsX
Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
  
 0.965
Tbis_3519
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: cvi:CV_3576 3-oxoacyl-(acyl-carrier protein) reductase.
 
 
 0.952
Tbis_1017
PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: 3-oxoacyl-(acyl-carrier-protein) reductase protein.
 
 
 0.949
Tbis_2373
PFAM: carboxyl transferase; KEGG: bsu:BSU23920 hypothetical protein.
    
 0.945
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
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