STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tbis_2957PFAM: NUDIX hydrolase; KEGG: sml:Smlt2194 hypothetical protein. (188 aa)    
Predicted Functional Partners:
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
 0.953
Tbis_2958
PFAM: Endonuclease/exonuclease/phosphatase; KEGG: afw:Anae109_1227 endonuclease/exonuclease/phosphatase.
       0.773
Tbis_2996
PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: cak:Caul_2746 DEAD/DEAH box helicase domain- containing protein; Belongs to the DEAD box helicase family.
  
 0.767
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
 0.649
Tbis_0748
TIGRFAM: F420-dependent oxidoreductase; PFAM: protein of unknown function DUF129; nitroreductase; KEGG: bpy:Bphyt_4255 F420-dependent oxidoreductase.
      0.634
Tbis_2956
Conserved hypothetical protein.
       0.613
Tbis_2954
PFAM: molybdopterin biosynthesis MoaE protein; KEGG: ade:Adeh_1120 molybdopterin synthase subunit MoaE / molybdopterin synthase subunit MoaD.
 
     0.547
Tbis_2955
PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; KEGG: dal:Dalk_1637 NAD-dependent epimerase/dehydratase.
   
   0.498
Tbis_2953
SMART: PDZ/DHR/GLGF domain protein; KEGG: bcr:BCAH187_A4038 PDZ domain protein.
       0.464
Tbis_0236
PFAM: Catalase domain protein; KEGG: abo:ABO_1845 catalase; Belongs to the catalase family.
    
  0.461
Your Current Organism:
Thermobispora bispora
NCBI taxonomy Id: 469371
Other names: T. bispora DSM 43833, Thermobispora bispora ATCC 19993, Thermobispora bispora DSM 43833, Thermobispora bispora str. DSM 43833, Thermobispora bispora strain DSM 43833
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