STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)    
Predicted Functional Partners:
Cwoe_1042
TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; KEGG: mxa:MXAN_6035 2-oxoglutarate dehydrogenase E1 component.
 
 0.999
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
Cwoe_4214
Succinate--CoA ligase (ADP-forming); PFAM: ATP-grasp domain protein; KEGG: bgl:bglu_1g29940 succinyl-CoA synthase, beta subunit.
 0.990
Cwoe_5285
KEGG: sun:SUN_1201 succinate dehydrogenase/fumarate reductase, iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin.
 0.990
Cwoe_5284
TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: nam:NAMH_1126 fumarate reductase flavoprotein subunit.
 0.988
Cwoe_5260
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ank:AnaeK_2724 succinate dehydrogenase/fumarate reductase iron-sulfur subunit.
  
 0.971
Cwoe_5261
KEGG: ank:AnaeK_2723 succinate dehydrogenase flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase.
 
 0.967
Cwoe_0745
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: tgr:Tgr7_0078 dihydrolipoamide acetyltransferase.
 
 0.960
Cwoe_4401
PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain- containing protein; E3 binding domain protein; KEGG: pla:Plav_1455 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase.
 
 0.959
Cwoe_4712
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: afw:Anae109_1891 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
  
 
 0.954
Your Current Organism:
Conexibacter woesei DSM 14684
NCBI taxonomy Id: 469383
Other names: C. woesei DSM 14684, Conexibacter woesei str. DSM 14684, Conexibacter woesei strain DSM 14684
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.