STRINGSTRING
aceA protein (Acinetobacter baumannii) - STRING interaction network
"aceA" - Isocitrate lyase in Acinetobacter baumannii
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceAIsocitrate lyase; Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; Derived by automated computational analysis using gene prediction method- Protein Homology (534 aa)    
Predicted Functional Partners:
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily (721 aa)
 
  0.992
acnB
Aconitate hydratase B; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the aconitase/IPM isomerase family (879 aa)
     
 
  0.944
eda
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein; Derived by automated computational analysis using gene prediction method- Protein Homology (206 aa)
         
  0.918
AIL78450.1
Bifunctional glyoxylate/hydroxypyruvate reductase B; Catalyzes the formation of glycolate from glyoxylate and glycerate from hydroxypyruvate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family (321 aa)
         
  0.916
AIL80305.1
Aconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method- Protein Homology (918 aa)
     
 
  0.915
AIL79653.1
Ureidoglycolate lyase; Catalyzes the formation of glyoxylate from (S)-ureidoglycolate; Derived by automated computational analysis using gene prediction method- Protein Homology (167 aa)
         
    0.800
AIL80251.1
Phosphate acetyltransferase; Derived by automated computational analysis using gene prediction method- Protein Homology (714 aa)
   
   
  0.728
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family (400 aa)
 
     
  0.710
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family (894 aa)
           
  0.664
gltA
Citrate synthase; Type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the citrate [...] (424 aa)
     
   
  0.599
Your Current Organism:
Acinetobacter baumannii
NCBI taxonomy Id: 470
Other names: A. baumannii, ATCC 19606, Acinetobacter baumannii, Acinetobacter genomosp. 2, Acinetobacter genomospecies 2, Bacterium anitratum, CCUG 19096, CIP 70.34, DSM 30007, JCM 6841, NCCB 85021, NCTC 12156
Server load: low (10%) [HD]