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ruvC protein (Acinetobacter baumannii) - STRING interaction network
"ruvC" - Crossover junction endodeoxyribonuclease RuvC in Acinetobacter baumannii
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5’-terminal phosphate and a 3’-terminal hydroxyl group (181 aa)    
Predicted Functional Partners:
ruvA
Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (199 aa)
 
 
  0.901
AIL77554.1
NAD(P)H-hydrate epimerase; Derived by automated computational analysis using gene prediction method- Protein Homology (486 aa)
   
        0.895
ruvB
Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (334 aa)
 
   
  0.865
AIL80356.1
DNA polymerase I; Has 3’-5’ exonuclease, 5’-3’ exonuclease and 5’-3’polymerase activities, primarily functions to fill gaps during DNA replication and repair; Derived by automated computational analysis using gene prediction method- Protein Homology (923 aa)
 
   
  0.789
yncA
N-acyltransferase YncA; Derived by automated computational analysis using gene prediction method- Protein Homology (181 aa)
   
        0.779
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3’- to 5’- polarity. Unwinds branched duplex DNA (Y-DNA) (681 aa)
   
   
  0.710
recJ
Single-stranded-DNA-specific exonuclease RecJ; Derived by automated computational analysis using gene prediction method- Protein Homology (566 aa)
 
 
  0.636
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (169 aa)
   
   
  0.629
AIL80089.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA (555 aa)
 
     
  0.626
AIL79989.1
ATP-binding protein; Derived by automated computational analysis using gene prediction method- Protein Homology (495 aa)
 
     
  0.625
Your Current Organism:
Acinetobacter baumannii
NCBI taxonomy Id: 470
Other names: A. baumannii, ATCC 19606, Acinetobacter baumannii, Acinetobacter genomosp. 2, Acinetobacter genomospecies 2, Bacterium anitratum, CCUG 19096, CIP 70.34, DSM 30007, JCM 6841, NCCB 85021, NCTC 12156
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