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cobA protein (Acinetobacter baumannii) - STRING interaction network
"cobA" - Siroheme synthase in Acinetobacter baumannii
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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cobASiroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme (457 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps; Belongs to the HMBS family (305 aa)
   
  0.989
AIL80035.1
Uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method- Protein Homology (255 aa)
   
 
  0.977
AIL78684.1
Uroporphyrinogen decarboxylase; Derived by automated computational analysis using gene prediction method- Protein Homology (357 aa)
   
 
  0.969
sir
Sulfite reductase [ferredoxin]; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family (547 aa)
 
 
  0.944
AIL81157.1
Nitrite reductase (NAD(P)H) small subunit; Derived by automated computational analysis using gene prediction method- Protein Homology (540 aa)
 
   
  0.944
AIL77374.1
Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the ALAD family (337 aa)
 
 
  0.921
AIL78755.1
Glutamate-1-semialdehyde 2,1-aminomutase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family (432 aa)
 
  0.906
AIL80524.1
Glutamyl-tRNA reductase; Derived by automated computational analysis using gene prediction method- Protein Homology (427 aa)
 
 
  0.902
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5’-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (351 aa)
 
   
  0.884
AIL81013.1
Rieske; Derived by automated computational analysis using gene prediction method- Protein Homology (102 aa)
   
   
  0.847
Your Current Organism:
Acinetobacter baumannii
NCBI taxonomy Id: 470
Other names: A. baumannii, ATCC 19606, Acinetobacter baumannii, Acinetobacter genomosp. 2, Acinetobacter genomospecies 2, Bacterium anitratum, CCUG 19096, CIP 70.34, DSM 30007, JCM 6841, NCCB 85021, NCTC 12156
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