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AIL79172.1 protein (Acinetobacter baumannii) - STRING interaction network
"AIL79172.1" - Bifunctional tetrahydrofolate synthase/dihydrofolate synthase in Acinetobacter baumannii
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
AIL79172.1Bifunctional tetrahydrofolate synthase/dihydrofolate synthase; Derived by automated computational analysis using gene prediction method- Protein Homology; Belongs to the folylpolyglutamate synthase family (428 aa)    
Predicted Functional Partners:
folP
Catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; Derived by automated computational analysis using gene prediction method- Protein Homology (283 aa)
 
  0.989
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA; Belongs to the AccD/PCCB family (298 aa)
 
   
  0.975
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (169 aa)
 
  0.961
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate; Belongs to the TrpA family (267 aa)
   
   
  0.897
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2’-deoxyuridine- 5’-monophosphate (dUMP) to 2’-deoxythymidine-5’-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis (280 aa)
   
 
  0.893
AIL79171.1
SPOR domain-containing protein; Derived by automated computational analysis using gene prediction method- Protein Homology (354 aa)
 
   
  0.887
folK
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method- Protein Homology (160 aa)
   
  0.881
folE
GTP cyclohydrolase 1; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method- Protein Homology (184 aa)
 
 
  0.778
sul2
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives (271 aa)
   
  0.645
AIL79994.1
Riboflavin biosynthesis protein RibD; Derived by automated computational analysis using gene prediction method- Protein Homology (361 aa)
     
   
  0.632
Your Current Organism:
Acinetobacter baumannii
NCBI taxonomy Id: 470
Other names: A. baumannii, ATCC 19606, Acinetobacter baumannii, Acinetobacter genomosp. 2, Acinetobacter genomospecies 2, Bacterium anitratum, CCUG 19096, CIP 70.34, DSM 30007, JCM 6841, NCCB 85021, NCTC 12156
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